Combining BET inhibitors and PARP inhibitors might help patients resistant to chemotherapy, the study suggests.

This can be accomplished by simply eliminating sequences homologous to proteins for which the structures are already known. Once such a list, which may number in the hundreds if not thousands 25 ...

LAE120 is a novel, allosteric and highly potent USP1 inhibitor, displaying monotherapy potency and combination activity with PARP inhibitor in HRD (homologous recombination deficiency) cancers. It has ...

Kelainan langka trisomi 13 atau Sindrom Patau bisa dialami sejak bayi di dalam kandungan. Lantas, bisakah kondisi ini dicegah?

Chromosomes are cellular structures that contain the genetic ... in promoting pairing and establishment of synapsis between homologous chromosomes.

Spacedust adapts the fast and sensitive structure comparisons of Foldseek and homology search capabilities of MMseqs2. It introduces a novel approach of aggregating sets of homologous hits between ...

This argues against the pedicel hypothesis where one would expect an earlier (before the two flanking flowers) formation of this structure. Late formation favours an alternative interpretation, namely ...

This all indicates that these structures and circuits are not homologous, but rather the result of convergent evolution, meaning that “they have independently developed these essential neural circuits ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, ...

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process ...

THE AIRLINE CHECK IN COUNTER TO BE DECLARED. WELL, NEW. AT FOUR THIS MORNING, TWO VEHICLES COLLIDED AND HIT A STRUCTURE IN YORK COUNTY. EMERGENCY DISPATCH SAYS IT HAPPENED ON WEST MIDDLE STREET ...

Ovarian cancer (OC) is the fifth most common cause of cancer-related mortality worldwide and represents the leading cause of death for gynecological malignancies. Nevertheless, over the last years, ...