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Organ transplantation offers life-saving treatment for patients with end-stage organ failure, restoring function and vastly ...
Berkeley scientists have developed a smartphone-based biosensor that mimics coffee-ring physics to detect disease proteins with exceptional sensitivity — but more research is needed before it reaches ...
Researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering have developed a compound that could work as a broad-spectrum drug targeting a range of coronaviruses. Their ...
The spike protein of the coronavirus, or SARS-CoV-2, binds to a receptor on the host cells, called ACE2, which allows the virus to enter the cells and infect it. Binding is the first step for ...
The team also discovered that a specific W682R mutation near the furin cleavage site in the viral spike protein may contribute to the enhanced infectivity and inflammation observed in the P7 strain.
We demonstrate that a conserved coronavirus spike protein peptide forms amyloid structures, differing from the native helical conformation and not predicted by amyloid aggregation algorithms. We ...