Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists ...

In a recent study, a group of researchers discuss the functional implications of this specific S protein mutation on SARS-CoV-2.

Scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system. The findings may help scientists ...

For most strains of SARS-CoV-2, the complete spike precursor protein is cleaved upon viral exit, freeing S1 to float and leaving the S2 attached to the transmembrane.

After demonstrating the interaction between the spike of SARS-CoV-2 and hepatocytes, the researchers studied the metabolic impact of this interaction using a battery of experimental procedures ...

SARS-CoV-2 spike protein persisted in the skull and brain, mouse and human autopsy data showed. In mouse models and human postmortem samples, SARS-CoV-2 spike protein was found in the skull marrow ...

The spike protein of SARS-CoV-2, the virus that causes COVID-19, has been the focus of a lot of research these past two years. It’s what the virus uses to invade host cells and it has been the ...

New research has uncovered a series of mutations in the SARS-CoV-2 spike protein that enhanced the virus' ability to infect the brains of mice. The findings may help scientists understand its ...

Scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system. The findings may help scientists ...

A new collaborative study between scientists at Northwestern University and the University of Illinois-Chicago uncovered a series of mutations in the SARS-CoV-2 spike protein that enhanced ...