Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic ...

The team confirmed that ZNF519 directly binds to the DNA of key cell cycle genes and acts as a repressor. Another protein, ZNF274, found in mammals but absent in older reptiles, fish etc, was found to ...

At the same time, the study uncovers a powerful defense mechanism within Salmonella itself, offering fresh hope for the development of phage-safe therapeutic strategies. This collaborative research ...

Moreover, this treatment modifies a globin repressor gene, which indeed causes reactivation of fetal globin, but may well have effects on other genes as well, with unknown consequences for the patient ...

Scientists successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers. The intermediate piece of DNA was cut out using CRISPR-Cas9 technology.

Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers. The intermediate ...

For the first time, researchers have identified a protein that represses the activity of energy-burning brown fat. The discovery opens the door to developing treatments for the extreme weight loss ...

Calreticulin, beyond its known role as a chaperone, also serves as an endoplasmic reticulum repressor of ATF6⍺, selectively regulating one arm of the unfolded protein response.

Introduction Cigarette smoking leads to altered DNA methylation at the aryl-hydrocarbon receptor repressor (AHRR) gene. However, it remains unknown whether pipe or cigar smoking is associated with ...

If the flowering-repressor protein bound to other gene regions in the plant’s genomic DNA, the scientists could pull the whole antibody-protein-DNA complex out of the solution to sequence those ...