Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a type of blood cancer that affects immune system cells. It most often affects the skin but can also involve bone marrow and other cell types.

Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that confers a predisposition to leukemic transformation and poor outcomes. 1 The exact incidence of BPDCN ...

A patient with a rare, aggressive, blastic plasmacytoid dendritic-cell neoplasm had tumor cells overexpressing BCL2 and had a response with a durable remission to venetoclax, a BCL2 inhibitor.

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound ...

Plasmacytoid dendritic cells can be activated with viral and bacterial DNA via TLR9. Activated pDCs promote generation of both Th1/Th17 cells [46,76,87,92] and Tregs [104,105].

Patients with blood cancers like polycythemia vera, a kind of myeloproliferative neoplasm, may benefit in learning more about ...

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells. Download PDF Copy; Reviewed. Ludwig-Maximilians-Universitaet Muenchen (LMU) Jul 18 2024.

Dendritic Cell Lineage Defined Date: April 6, 2009 Source: Rockefeller University Summary: Dendritic cells were discovered more than 30 years ago, but their pedigree has never been fully charted.

Oncotarget published "Activation of plasmacytoid dendritic cells promotes AML-cell fratricide" which reported that Interferons have been previously shown to aid in the clearance of AML cells. Type ...

Introduction. Since the early reference to plasmacytoid dendritic cells (pDCs) in the paracortical area of reactive lymph nodes in 1958 by Lennert and Remmele, [] an abundance of new information ...