This important study aims to understand the role of endothelial cell differentiation into pericytes in the restoration of blood-brain barrier function after ischemic stroke. Identification of ...

Learn how nanoparticles cross the blood-brain barrier (BBB) and explore their potential in treating neurological disorders ...

The blood-brain barrier is a network of blood vessels and tissues that acts as a protective shield, preventing harmful substances in the blood from reaching the brain. In Alzheimer’s disease, this ...

Here are five recent innovative bioprinting and bioink studies that are building synthetic biological structures.

Indeed, when Chen and colleagues analyzed cells in the choroid plexus using single-cell RNA-Seq, they found greater senescence in numerous cell types, including epithelial, endothelial, and smooth ...

Here, we uncovered a positive correlation between the presence of pericytes in the tumor-associated vasculature and TNFα-induced leakage and drug delivery, especially when drugs were encapsulated in ...

For example, fibroblast activation protein (FAP) is selectively expressed by CAFs and pericytes in about 90% of human epithelial cancers. Given the high expression and restricted distribution of FAP, ...

To some extent, the pericytes and astrocytes appended to the cerebral microvessels participate to the establishment of the barrier properties associated with the cerebral endothelium. The barrier ...

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