BPDCN is an aggressive hematologic malignancy with a historically poor prognosisVisualDx is a clinical decision support system used by more than ...

An expert discusses how blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy derived from ...

No writing assistance was utilized in the production of this manuscript. Plasmacytoid dendritic cells (pDCs) are specialized APCs. Compared with other APCs, pDCs express a high level of TLR9 and ...

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast ...

Researchers have uncovered critical mechanisms linked to metabolic insufficiencies that underlie plasmacytoid dendritic cell ...

goblet-cell hyperplasia and bronchial hyper-reactivity. Dendritic cells (DCs) sample the airway luminal content for the presence of allergens by crossing the airway epithelial-cell barrier.

Zúñiga believes that interventions that target LDHB or related metabolic pathways could be explored as a way to counteract ...

An expert discusses how medical professionals have integrated tagraxofusp into blastic plasmacytoid dendritic cell neoplasm (BPDCN) treatment, leveraging its CD123-targeted efficacy per 0114 trial ...

As the researchers demonstrate, dendritic cells that are marked by expression of the transcription factor RORγt—so-called RORγt + dendritic cells (DCs)—are found in many tissues. Moreover ...

Although many questions need to be addressed, modulation of pDC function has become a possible ... of this manuscript. Plasmacytoid dendritic cells (pDCs) are specialized APCs.