A bone marrow analysis conducted 2 months later showed approximately 4.3% myeloblasts of nucleated cells, as well as multinucleated erythroblasts; furthermore, pathologists observed megakaryocytes ...
Erythropoiesis is a critical homeostatic process responsible for the production of red blood cells, essential for oxygen delivery to tissues. This review provides a brief overview of erythropoiesis: ...
The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.nanolett.5c00324. Experimental details regarding sample synthesis ...
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We demonstrate, for the first time, normalized expression of the iron chaperones Pcbp1 and Ncoa4 and increased ferritin stores in late-stage erythroblasts from deferiprone-treated MDS mice, evidence ...
The development of haematopoietic stem cells into mature erythrocytes – erythropoiesis – is a controlled process characterized by cellular reorganization and drastic reshaping of the proteome ...
murine model was due to reduced proliferation of megakaryocyte erythroid progenitors and increased apoptosis of erythroblasts. Colony-forming cell assays indicated that the leukemic bone marrow ...