A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a ...

A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a ...

Research clarifies nuclear hormone receptor function in plants. Chinese Academy of Sciences Headquarters. Journal Proceedings of the National Academy of Sciences DOI 10.1073/pnas.1710885114.

For this article, Nadia S. Halim interviewed Ronald Evans, professor in the gene expression laboratory, Salk Institute, La Jolla, Calif., and Hongwu Chen, postdoctoral fellow, Salk Institute. Both are ...

September 15, 2008 (Vol. 28, No. 16) New Technology Was Designed for Screening and Profiling Applications DiscoveRx has developed a cell-based nuclear hormone receptor (NHR) assay using its enzyme ...

Nuclear hormone receptors are transcription factors that regulate multiple biological pathways and may provide protection against metabolic, inflammatory and cardiovascular diseases. In this ...

The striking capacity for plants to adapt their growth and development to an ever-changing environment is mediated by diverse plant hormones that regulate virtually every aspect of plant life. In ...

In the 1980s, Evans led the landmark discovery of a family of proteins he named "nuclear hormone receptors." These hormone-activated receptors attach themselves to our DNA and control which genes ...

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development ...