Optimizing guide RNA design for Cas13. With data from massively parallel screens, Wessels et al. develop computational models to identify optimal guide RNAs for the RNA-targeting CRISPR enzyme Cas13d.

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...

Powerball winning numbers are in for the Saturday, Dec. 20 drawing with a jackpot that reached an estimated $1.43 billion ($659.3 million cash option). The winning numbers in Saturday's drawing are 4, ...

Just in time for the holidays, the Powerball jackpot is now at a staggering $1.5 billion, the 5th largest in the lottery’s history. If a ticket matches all five numbers plus the Powerball on Saturday, ...

The next Powerball jackpot is an estimated $1.50 billion after no one won Wednesday's drawing. This jackpot ranks as the fifth-largest in Powerball history and the seventh-largest overall in the U.S.

Feeling stuck on today’s puzzle? We can help. By New York Times Games Hi, busy bees! Welcome to today’s Spelling Bee forum. Enter the comments section to see hints, conversation, helpful tips and ...

Julia Kagan is a financial/consumer journalist and former senior editor, personal finance, of Investopedia. Skylar Clarine is a fact-checker and expert in personal finance with a range of experience ...