Before each cell division, termed mitosis, the genetic information must first be duplicated. This ensures that each chromosome in the cell that is ready to divide receives two copies of genetic ...

The human body is made up of billions of cells. These cells grow and divide through a process called cell division. There are ...

Before each cell division, termed mitosis, the genetic information must first be duplicated. This ensures that each chromosome in the cell that is ready to divide receives two copies of genetic ...

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a ...

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A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Correct mitotic spindle alignment is essential ...

whereby mutant cells transit through an intermediate metastable state, that requires their capacity to enter mitosis. We report here that Notch signaling is a gatekeeper of luminal cell fate and that ...

However, the mechanistic role of PCNA in HCC progression remains poorly understood. This study aimed to investigate how PCNA regulates DNA damage repair and cell cycle progression in HCC, with a focus ...