Genetic code reveals how mutations disrupt mRNA and cause disease

An international team led by Monash University researchers has uncovered the genetic code governing the way genetic mutations ...
EurekAlert!

U of I researchers trace genetic code’s origins to early protein structures

URBANA, Ill. – Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function. But how and why did it come to be the way ...
chromatographyonline

Challenges and Solutions in Oligonucleotide Analysis, Part I: An Overview of Liquid Chromatography Methods and Applications

The rise in therapeutic oligonucleotides has increased research into chromatographic methods for their analysis and purification, presenting new challenges for analysts. Various chromatographic ...
C&EN

How RNA helped build life’s first proteins

Life may have first emerged in deep sea thermal vents or surface hot springs (Yellowstone National Park’s Grand Prismatic Spring is shown here). New research shows how high-energy thioesters could ...
Yahoo

Messenger RNA could be the key to an HIV vaccine — but RFK Jr.'s cuts pose a threat

The quest for a vaccine against HIV has been going on for about 40 years — almost as long as the virus that causes AIDS has been known to scientists and the public. There has been some progress ...
News Medical

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain ...
Morningstar

Children's Hospital of Philadelphia Researchers Find that Missing Messenger RNA Fragments Could be Key to New Immunotherapy for Hard-to-Treat Tumors

PHILADELPHIA, Aug. 15, 2025 /PRNewswire/ -- A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric ...
The New York Times

Transfer news live updates: August 13 latest on Liverpool's Isak and Guehi efforts, plus Donnarumma's next move

Clubs in the Premier League and across Europe are still scrambling to bolster their squads ahead of this summer’s transfer deadline. Fresh deals continue to emerge while there are plenty of existing ...
FierceBiotech

Flagship Pioneering's Alltrna sheds staff as it readies for clinical debut

Alltrna, the preclinical Flagship Pioneering-backed biotech trying to turn transfer RNA (tRNA) into drugs, is slimming down as it works toward the clinic. The Massachusetts-based outfit has laid off ...
STAT

Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research

Helen Branswell covers issues broadly related to infectious diseases, including outbreaks, preparedness, research, and vaccine development. Follow her on Mastodon and Bluesky. You can reach Helen on ...
Phys.org

Where did RNA come from? Origin-of-life scientists help to answer the question

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...
The National Law Review

One Big Beautiful Bill: Estate and Gift Tax Exclusion and the Generation-Skipping Transfer Tax Exemption Increases to $15 Million

We collaborate with the world's leading lawyers to deliver news tailored for you. Sign Up for any (or all) of our 25+ Newsletters. Some states have laws and ethical rules regarding solicitation and ...