T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

The authors investigated the potential role of IgG N-glycosylation in Haemorrhagic Fever with Renal Syndrome (HFRS), which may offer significant insights for understanding molecular mechanisms and for ...

We found that pre-existing IgM and IgG antibodies cross-reactive with SARS-CoV-2 antigens on the rapid tests were present in 32% of pre-pandemic serum samples from our Zimbabwean study populations.

The test is used for the detection of antibodies against Borrelia burgdorferi in serum from patients with signs, symptoms, and clinical history consistent with Lyme disease.

Objectives: Polyneuropathies with associated serum IgM antibodies are often difficult to treat. Rituximab is a monoclonal antibody directed against the B cell surface membrane marker CD20. Rituximab ...

Aurinia Pharmaceuticals Inc. has announced positive results from a Phase 1 single-ascending-dose (SAD) study of aritinercept (AUR200), its dual inhibitor of B cell-activating factor (BAFF) and a ...

IgG antibodies originate from plasma cells that have undergone B-cell maturation with the help of T FH cells in germinal centers, which causes a switch from low-affinity IgM to high-affinity IgG. 146 ...