Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

A dual-drug hydrogel using dexamethasone and kartogenin supports cartilage repair by controlling inflammation and promoting ...

Objectives Single-cell and spatial transcriptomics analysis of human knee articular cartilage tissue to present a comprehensive transcriptome landscape and osteoarthritis (OA)-critical cell ...

Osteoarthritis is driven by the irreversible degradation of hyaline cartilage in the joints which eventually leads to pain and disability with complete joint replacement being the standard ...

The authors conclude that exercise protects the articular cartilage intermediate zone and the associated upregulation of CILP facilitates Keap1-Nrf2 interaction to prevent chondrocyte ferroptosis and ...

Our experiments have proven that, compared with the control group, GELMA/PEGDA + KGN repaired cartilage defects and restored cartilage to hyaline cartilage. Our study suggests that implementing ...

Scientists at Northwestern University have developed a new bioactive material that can regenerate damaged cartilage in joints. This material, which looks like a rubbery goo, has successfully grown ...

“We found that the hybrid scaffold placed in osteochondral defects in sheep—an animal model whose joints experience similar loading to humans—induced repair of hyaline cartilage in ...

Professor Samuel I. Stupp developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model.

Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model. Although it looks like a ...