Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for ...

An organism has multiple, cell type-specific, epigenomes comprising epigenetic marks such as DNA methylation, histone modification and specifically positioned nucleosomes. Here, the authors ...

Our group retains an interest in the areas of structure-function studies of RNA interference mediated by siRNA pathway, and on post-translation histone and DNA modifications ... Molecular basis of ...

To investigate genetic and epigenetic issues stimulating the evolution of primary trastuzumab resistant and sensitive breast cancer, we compared genomic variation, histone modification and DNA ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Additional data presented will underscore the potential of GRAIL's ctDNA-based targeted methylation assay for quantifying abnormal promoter methylation, which is a known hallmark of cancer and has ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

View Full Profile. Learn about our Editorial Policies. DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in ...

Mar. 26, 2025 — Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the ...

Longitudinally measuring and forecasting changes in DNA methylation can reveal patterns of ageing and disease progression, but biosamples may not always be available. We introduce a probabilistic ...