Hereditary persistence of fetal hemoglobin is a condition in which levels of HbF persist at levels greater than typically expected (less than 1%).

The action of BCL11A at the γ-globin promoter, together with the analysis of rare variants elsewhere in the promoter that cause hereditary persistence of fetal hemoglobin, suggests that ...

We found a new (δβ) 0-thalassemia deletion and a rare hereditary persistence of fetal hemoglobin deletion with identical downstream breakpoints.Comparison of the two deletions resulted in the ...

Hereditary persistence of fetal hemoglobin is exactly what it sounds like – instead of completely shutting down fetal hemoglobin production after birth like most people do, ...

BEAM-101 BEACON Trial Represents the First Clinical Trial of a Base Editor in the United StatesCAMBRIDGE, Mass., Nov. 14, 2022 (GLOBE NEWSWIRE) -- Beam Therapeutics Inc. (Nasdaq: BEAM), a ...

Those people have what is called hereditary persistence of fetal hemoglobin, something that all infants have, though most people’s blood switches over to adult hemoglobin at around 6 months old.

FLT1 is among 14 new genetic markers of fetal hemoglobin the scientists identified from GWAS data gathered and used with permission from 3,751 people with sickle cell disease.

Those people have what is called hereditary persistence of fetal hemoglobin, something that all infants have, though most people’s blood switches over to adult hemoglobin at around 6 months old.

Treatment with BEAM-101 demonstrated robust and durable increases in fetal hemoglobin (HbF) and reductions in ... of naturally occurring variants seen in hereditary persistence of fetal hemoglobin.