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Metabolic-associated steatohepatitis (MASH) is an advanced and progressive liver disease that potentially causes cirrhosis ...
The identities of the degradation products following catabolism were confirmed by MALDI-MS and LC−MS, showing that porphyrin catabolism was regioselective at the α-position. Finally, through the ...
In flavocytochrome P450 BM3, there is a conserved phenylalanine residue at position 393 (Phe393), close to Cys400, the thiolate ligand to the heme. Substitution of Phe393 by Ala, His, Tyr, and Trp has ...