L ast week in First Opinion, six experts explored the use of gene editing to fix a defective gene in a sperm or egg cell, or in an embryo that’s only a few days old.This technique, called ...

The council’s openness to human germline editing was notable, however. Because of the Nazis’ eugenics programs and horrific human medical experiments, Germany has historically been even warier ...

A new study by researchers at the Hebrew University of Jerusalem (HU) has revealed unexpected and sex-specific effects of germline regulation on longevity.

Five arguments for germline genome editing Immediacy. Through GGE we can treat some genetic conditions that are beyond the current ability of traditional medicines, such as Alzheimer’s disease ...

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates. Contrary to classical evolutionary theories, it turns out that ...

In the graphic, I use a germline BRCA2 mutation as an example. But there are actually over 50 known hereditary cancer syndromes caused by different germline mutations, according to the National Cancer ...

Accurate genomic profiling is essential for clinical decision-making and optimizing treatment recommendations. Tumor-only sequencing has been adopted by many laboratories to guide precision ...

“It’s known that germline structural variation also can contribute to the molecular profile of cancers,” Creighton said. “Here we study the extent of its contribution.” The researchers worked with ...

Undergoing germline testing is of particular importance for patients with prostate cancer, as one expert explained. “Germline testing is that genetic testing of the of the sequence of DNA that you ...

Key Takeaways. Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM ...

Drs Sandhya Srinivas and Heather Cheng discuss PARP inhibitors, clinical trials, and germline vs somatic testing for patients with prostate cancer, as well as the optimal time for this testing.