Inherited repeat mutations in the HTT gene expand in neurons over decades ... This can happen both in cells of the germ line (which form sperm and egg cells) and in somatic cells (cells of the ...

And it is at this intersection that the future of medicine is being written, with innovations like CRISPR and CAR-T therapy unlocking ... of guidelines that banned germline editing.

Genetic testing, via germline and somatic testing, is crucial in breast cancer to understand inherited risks and tumor ...

For example, some patients with kidney cancer with specific gene mutations may benefit from targeted therapy, while those with stage 4 ... such as von Hippel Lindell (VHL) germline mutations. If they ...

As genetic and biomarker tests become more common, so do new therapies that target specific tumor types and may lead to better outcomes ...

In an earlier study, patients with biomarker-positive high-grade glioma lived longer after treatment with DB107 than biomarker-negative patients.

Treatment can include surgery, radioactive iodine, chemotherapy, radiation, and targeted therapy. Thyroid cancer is caused by ... People with medullary cancer may have a germline mutation, so family ...