The germinal centers that form in the body's lymph nodes work as a fitness boot camp in which B cells evolve to produce antibodies of increasingly higher affinity to an invading pathogen. This new ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Continuous germinal center invasion contributes to the diversity of the immune response. Cell , 2023; 186 (1): 147 DOI: 10.1016/j.cell.2022.11.032 Cite This Page : ...

Multi-center project will profile over 40,000 samples using ultra-sensitive NULISA™ technology. How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis Discover how Alderley ...

Germinal centers form in the body's lymphatic tissues shortly after vaccination or infection. Once inside a germinal center, B cells undergo rapid mutations and, ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...

Germinal centers are made up of two distinct regions – the light zone and dark zone, with some cells located in specific areas, and others which move between the zones.

The prognostically favorable germinal-center B-cell gene-expression signature is notable because cell lines derived from germinal-center B-cell–like diffuse large-B-cell lymphomas have decreased ...