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Data Centers’ Hunger for Energy Could Raise All Electric Bills Individuals and small businesses may end up bearing some of the cost of grid upgrades needed for large electricity users, a new ...
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
A phase 2 expansion in patients with germinal-center B-cell (GCB) and non-GCB DLBCL was performed. ViPOR was administered every 21 days for six cycles.
Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.
A diverse immune response hinges on naive B cells mingling with high affinity ones in the late-stage germinal center. Whether that helps or hinders, however, depends on the virus.
Germinal centers form in the body’s lymphatic tissues shortly after vaccination or infection. Once inside a germinal center, B cells undergo rapid mutations and, through a process of natural ...
While most germinal centers shut down after a few weeks, some stay in business for more than six months. A new study helps explain why.
If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons ...
Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells undergo antibody affinity maturation and clonal expansion.
Ed Baierlein, who founded Germinal Stage Denver in 1973 and oversaw pretty much every decision at the theater, from play selection to casting, outreach to finances and staging to site selection ...
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