Ganglioside GM1 accumulated in the brain was visualized in frozen sections by immuno-staining of avidin:biotinylated enzyme complex method with anti-GM1 ganglioside monoclonal antibody conjugated ...

Study published in JCI also found hidden binding sites that cause neuropathy. Scientists at the University of Glasgow have found that both mouse and human GMI-specific antibodies can damage live ...

NEW YORK, and DURHAM, N.C., Sept. 09, 2021 (GLOBE NEWSWIRE) -- Sio Gene Therapies Inc. (NASDAQ: SIOX), a clinical-stage company focused on developing gene therapies to radically transform the ...

Lysogene announced that the Food and Drug Administration (FDA) has granted orphan designation to LYS-GM101, their gene therapy drug candidate for the treatment of GM1 Gangliosidosis (GM1).

Initial data from the ongoing Phase 1/2 study in five patients in the low-dose cohort showed that AXO-AAV-GM1 was generally well tolerated with a favorable safety profile and provide early ...