Patients’ serum and cerebrospinal fluid (CSF) samples were tested for neural autoantibodies by immunohistochemistry on mouse and rat brain sections, by cell-based assays (CBA) and immunoblot. GFAP ...

Intraperitoneal injection of LPS (250 µg/kg every alternative day for a total of seven doses over 14 days) triggered glial cell activation, neuroinflammation, oxidative stress, and neurodegeneration ...

Glial fibrillary acidic protein (GFAP) levels peak around 24 hours after traumatic brain injury (TBI) 2. Higher GFAP levels ...

For instance, some brain processes could contribute to memory ... All example trials are taken from the same mouse and session. Credit: Nature Neuroscience (2025). DOI: 10.1038/s41593-024-01859-1 ...

Jan. 30, 2025 — People with brain bleeds had nearly 7 times higher blood levels of a specific brain protein, called glial fibrillary acidic protein (GFAP), than ... Jan. 24, 2025 — A new study ...

This is the first time that brain tissue has been cryogenically frozen and revived without damage. In a process called vitrification, researchers treated slices of mouse brains with ...

They then measured the concentrations of five molecular markers that previous research suggested might hold promise for diagnosing brain injuries: GFAP, neurofilament light chain, amyloid-beta 40 ...

Here, we identified a circuit, locus coeruleus descending noradrenergic neurons projecting to the spinal dorsal horn (LC →SDH -NA neurons), that is activated by acute exposure to restraint stress and ...

Their findings, published in Brain Communications, suggest that GFAP could serve as a biomarker for stroke and brain injuries, potentially leading to faster and more accurate diagnoses through blood ...

the integrity of brain synapses or on brain markers of Alzheimer’s. The results, said Madeline Wood Alexander, the study’s lead author and a doctoral student at Sunnybrook Research Institute ...