CCL3 inhibited erythroid differentiation of hematopoietic stem cells, common myeloid progenitors and especially megakaryocytic-erythroid progenitors. Administration of the CCR1 antagonist ...

Low plasma erythropoietin (EPO) levels are a major factor in anemia of prematurity. Erythroid progenitors from neonates have responded well to EPO in vitro, (studies performed outside a living ...

We examine the role of glucocorticoids (GCs) in modulating this process, highlighting how they influence erythroid progenitor proliferation and differentiation through various mechanisms, including ...

Erythropoietin is a naturally occurring glycoprotein hormone, also known as a growth factor, produced in the kidneys that ...

Hemoglobin synthesis in the developing erythroblasts requires iron-containing heme. While EPO allows survival of erythroid progenitors and early-stage erythroblasts by activating transcription of anti ...

Thyroid hormones stimulate the proliferation of erythroid progenitor cells either directly or by increasing the production of erythropoietin. Second, bleeding may have occurred, further reducing HCT ...

Dr. Daniel Leonard (Medicine): A 65-year-old woman was transferred to this hospital for evaluation of pancytopenia and back pain. The patient had been in her usual state of health until 3 weeks ...

NAINR. 2004;4(4):231-239. Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis, condition in which the majority of erythrocytes are ...

NAD deficiency perturbs embryonic development resulting in multiple congenital malformations, collectively termed Congenital NAD Deficiency Disorder (CNDD). The authors report fundamental findings ...

Department of Cardiology, Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital affiliated to Shanghai Jiaotong University School of ...

Objectives The administration of androgen deprivation therapy (ADT) to patients with metastatic prostate cancer might be associated with some adverse effects such as anaemia; however, few studies have ...