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Activators of nuclear factor-erythroid 2-related factor 2 (NRF2) could lead to promising therapeutics for prevention and treatment of oxidative stress and inflammatory disorders. Ubiquitination and ...
As autophagy has been implicated in the removal of mitochondria in erythroid development (12, 13), we investigated the ability of Atg7−/− cells to lose their mitochondria.
WT-4 exhibits mRNA changes that are characteristic of erythroid maturation, including induction of α-globin and band 3, and concommitant downregulation of Gata-2.
Many viruses undergo large-scale conformational changes during their life cycles. Blocking the transition from one stage of the life cycle to the next is an attractive strategy for the development of ...
Despite the increasing interest in cardiac autonomic nervous activity, the normal development is not fully understood. The main aim was to determine the maturation of different cardiac sympathetic‐ ...
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