Bristol Myers Squibb has announced positive topline results from its phase 3 trial of Reblozyl (luspatercept-aamt), the first erythroid maturation agent for first-line treatment of patients with ...

If approved, it would compete with Bristol-Myers Squibb’s erythroid maturation agent Reblozyl (luspatercept), which was cleared to treat anaemia in adults with low-risk, relapsed MDS in 2020 and ...

Researchers show that cordycepin, a compound from Cordyceps militaris, can boost endurance and protect brain function in mice ...

This review provides a brief overview of erythropoiesis: the maturation of hematopoietic stem cells to circulating red blood cells. We examine the role of glucocorticoids (GCs) in modulating this ...

In addition, the development of novel tools ... EPO binding to EPO receptor on erythroid precursors in the bone marrow in turn induces their survival, cell division, and differentiation to ultimately ...

Thyroid hormones stimulate the proliferation of erythroid progenitor cells either directly or ... However, a decrease in Tregs function can result in the loss of this tolerance and the development of ...

Lyfgenia uses a lentiviral vector to synthesise haemoglobin production in erythroid precursor cells ... Last summer, researchers reported the development of an oral therapy that could be used to ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Lego is working to build up its in-house game development, the company's boss has revealed. Speaking to The Financial Times, Lego boss Niels Christiansen said the company was increasing its focus ...

“The pain of disillusionment is real, but ridding ourselves of the cancerous memecoin sector—which was in hindsight tremendously unfair—is a good development overall,” he wrote. Read ...