Colony-forming cell assays indicated that the leukemic bone marrow (BM) plasma inhibited erythroid colony formation, whereas they had no inhibitory effect on other types of colonies. Cytokine ...

The cellular enzyme is overexpressed in up to 90% of cancers, but is almost always absent in normal cells, with a few ... (MF), another form of bone marrow cancer, and expects data from the ...

EPO binding to EPO receptor on erythroid precursors in the bone marrow in turn induces their survival, cell division, and differentiation to ultimately enucleate, producing reticulocytes that mature ...

Late-stage normoblasts in the erythroid series were decreased ... The immunophenotype was consistent with systemic mastocytosis, suggesting mast cell leukemia. Figure 3. Bone marrow chromosome ...

Additionally, hypothyroidism suppresses bone marrow activity, reducing erythropoiesis, which can result in non-regenerative anemia. Thyroid hormones stimulate the proliferation of erythroid progenitor ...

Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now, ...

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

Long-lived plasma cells (LLPCs), which are important for protection from reinfection, are thought to migrate specifically to the bone marrow. "The importance of LLPCs to immunity is well known ...

A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer centers. A bone marrow transplant process co ...

New research shows that mutations in DNMT3A in blood stem cells of frequent blood donors may bolster the production of noncancerous cells.