Interferon regulatory factor 5 (IRF5) is a transcription factor activated downstream of Toll-like receptors (TLRs) 7, 8 and 9, and is predominantly expressed in dendritic cells, B cells, monocytes and ...

The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...

Studies presented at the ASCO Annual Meeting 2025 highlighted immunotherapies that may provide new standards of care for certain cancers as well as immunotherapies that are breaking new ground by ...

New studies are revealing how psychedelics interact with neural circuits, receptor systems, and psychological processes in ways that may support lasting mental health improvements. By combining brain ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Glial cells support neurological structures, function, cognition, behaviours, physical skills, and motor coordination.

Experimental treatment could offer a safer, cheaper alternative to CAR-T-cell therapies for disorders such as lupus.

LMU researchers have shown that a particular type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches. As part of the innate immune system, ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia ...