Small molecules, big role: Interactive database illustrates how snoRNAs function in gene regulation
Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and association with certain ...
EurekAlert!2d
Small molecules, big role: snoRNAs in gene regulation
Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer, ...
eLife2d
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
Frontiers16d
Tumor microenvironment and exosomes in brain metastasis: Molecular mechanisms and clinical application
Metastasis is one of the important biological features of malignant tumors and one of the main factors responsible for poor prognosis. Although the widespread application of newer clinical ...
eLife24d
Genetic Inactivation of the β1 adrenergic receptor prevents Cerebral Cavernous Malformations in zebrafish
In this important study, the authors test the model that a type of vascular lesion caused by the inactivation of one gene in the cells that line blood vessels requires the activity of a second gene ...
The Lancet16d
Biliary Atresia – emerging diagnostic and therapy opportunities
2Dr. Li Dak-Sum Research Centre, the University of Hong Kong, Hong Kong 3Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 4Department of Surgery, ...