When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

By Abhishyant Kidangoor Tyler Kartzinel likens protecting biodiversity to enhancing cellphone networks. His analogy is pretty straightforward: look for gaps in coverage, and then do what’s needed to ...

But the new study used advanced sequencing technologies to reveal the most rapidly changing regions of human DNA—regions that Quinlan describes as “previously untouchable.” “We saw parts of our genome ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

1. Describe the role of DNA methylation in gene regulation, development, and disease progression. 2. Compare computational methods used to analyze DNA methylation signals from long-read sequencing ...

Comprehensive genome sequencing across four generations reveals that certain regions of human DNA mutate much more rapidly than previously recognized, with nearly 200 new genetic changes per ...