CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about ...

Rare genetic diseases are challenging for patients and their families—made all the more overwhelming because symptoms tend to ...

CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, there’s no more than ...

But CRISPR-Cas now appears to go even further than cutting DNA. “When we discovered CRISPR-Cas, we observed that it cuts viral DNA in precise locations,” explains Brouns.

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them ...

CRISPR-Cas will eventually be used for gene therapy – to repair mutated genes that cause disease – but to make it safer, anti-CRISPRs are needed to modulate the technology.

A n international research group, with the participation of UPF, has for the first time reconstructed ancestors dating back 2.6 billion years of the well-known CRISPR-Cas system, and studied their ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to treat ...