Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the genome.

Rare genetic diseases are challenging for patients and their families—made all the more overwhelming because symptoms tend to ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about ...

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to ...

Researchers from TU Delft in the group of Stan Brouns have discovered a CRISPR-Cas system that cuts proteins instead of DNA. The discovery opens the door to the development of a range of ...

Virginijus Šikšnys studies the diversity of CRISPR systems found in nature. (Image credit: Vilnius University) Nicoletta Lanese: Could you describe when you first began working with CRISPR-Cas?

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to ...