Microglial activation is a determining factor that allows amyloid-beta accumulation to drive reactive astrogliosis, amplifying inflammatory responses in the brain. This was the conclusion of a study ...
A shared passion for conquering multiple sclerosis (MS) brought together a visionary inventor and a leading neurological scientist at Case Western Reserve University. Today, their shared vision is ...
Glial cells, also known as neuroglia, are non-neuronal cells that play a crucial role in various neurophysiological processes. They not only support nervous system structures but also contribute to ...
An estimated 86 billion neurons in the average human brain govern our body’s functions and conjure — somehow — the human mind. C. elegans has 302 neurons in one sex and a few more in the other.
Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal ...
Enhanced glucose uptake in glial cells might help fight AD. In Alzheimer’s disease and related neurodegenerative diseases, excess activation of glial cells causes neuroinflammation and damage to ...
Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and ...
Diminishing energy production in aging neurons triggers senescence in nearby glial cells, which ordinarily support and protect neurons. With age, some cells in the brain enter a state of senescence: ...
The amyloid cascade—plaques to tangles to cognitive decline—has become well established. Less well understood is what role inflammation and glial changes play. Now, by analyzing single-nuclei RNA-Seq ...
Gliomatosis cerebri (GC) refers to a certain growth pattern of a glial tumor that is widespread and affects multiple sections of the brain. GC is a tumor that begins in the central nervous system (CNS ...
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