2024 — Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the ... New Gene Drive ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

CRISPR-Cas systems are prokaryotic immune systems that ... survival and for terminal erythroid differentiation. Gene-edited mouse models are crucial for disease research but remain challenging ...

Meanwhile, Vertex and CRISPR presented new data on 31 patients with SCD who had been suffering a median of four vaso-occlusive crises (VOCs) – painful attacks that are associated with the ...

Bayer is to set up a joint venture with CRISPR Therapeutics and acquire a minority stake in the firm, one of the pioneers in the potentially revolutionary gene-editing technology. The partnership ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In efforts to identify additional therapeutic ...

Cells change their metabolic profiles in response to underlying gene regulatory networks, but how can alterations in metabolism encode specific transcriptional instructions? Here, we show that forcing ...