This is achieved by infecting a pool of Cas9- expressing cells with ... sequencing datasets that emerge from each single-cell CRISPR screen. “These days, we routinely create close to 10 billion ...

A pool would simplify this process by creating “a one-stop shop for commercial users.” The firm licensing the CRISPR patent pool ... bacterial and yeast cell culture and other applications.

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

The method, called "Perturb-multiome," uses CRISPR to knock out the function of individual transcription factors across many blood cells at once. The researchers then perform single-cell analyses ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years ... and an affiliate of Yale Cancer Center, Yale Stem Cell Center, and Yale Center for Biomedical Data Science.

CRISPR and Vertex's two phase 1/2 studies in thalassaemia and SCD – called CLIMB-111 and CLIMB-211, respectively – have now recruited 19 patients. They are due to enrol 45 apiece, and are ...