Experts warn that difficulty swallowing, producing excess saliva or even drooling could be a sign of motor neurone disease (MND).  The progressive condition affects the brain and nerves that ...

One challenge in developing effective therapies has been the difficulty in objectively measuring disease progression and ...

Motor neuron diseases are a group of fatal progressive disorders that rob the body and brain of the ability to function.

One challenge in developing effective therapies has been the difficulty in objectively measuring disease progression and treatment response ... The study also confirmed that patients with bulbar-onset ...

The primary efficacy outcome was measured using the disease rate ratio (DRR), a statistical model incorporating ALS disease severity, functional decline, and survival outcomes. A DRR below 1 would ...

Spinal and bulbar muscular atrophy (SBMA ... diseases such as CMT and also to correlate with disease progression rate in ALS. Intriguingly, NF changes were not detected in SBMA patients and mouse ...

NEW research has shown that tetramethylpyrazine nitrone is safe for patients with amyotrophic lateral sclerosis (ALS ... disease progression, showing an improvement of 3.63 kg (95% CI, 0.84-6.41 kg).

In patients with progressive bulbar ALS, 4/7 subjects had an abnormal epiglottis ... that positive pressures more easily trigger laryngeal adductor reflexes in a disease that is predominantly spastic.

it is also observed in bulbar onset ALS as well as patients in early stages of the disease as defined by functional deficits, making it a potentially important diagnostic indicator.4 5 A potential ...

Columnist Dagmar Munn says she has often felt out of place in the ALS community because of the slower pace of her disease ...