Graphical Abstract Multiple layers of vascular smooth muscle cells (vSMCs) are present in blood vessels forming the media of the vessel wall. vSMCs provide a vessel wall structure, enabling it to ...

Perhaps the most prominent examples are the elimination of photoreceptor outer segments from photoreceptor cells by the retinal pigment epithelium, 124, 125 and the uptake of erythroblast nuclei by ...

Erythroblast Island Macrophages (EIMs) are specialized cells that play a crucial role in erythropoiesis by forming erythroblastic islands (EBIs) and supporting the maturation of erythroblasts. These ...

Intrinsically disordered protein regions (IDRs) are structurally dynamic yet functional, often interacting with other proteins through short linear motifs (SLiMs). Proline residues in IDRs introduce ...

Luspatercept, an erythroid maturation agent, promotes late-stage erythroblast expansion and differentiation, enhancing red blood cell production. 2 The study defined the primary end point as the ...

Hairy-cell leukemia, a rare B-cell cancer driven by a BRAF mutation and manifesting with cytopenias and splenomegaly, is responsive to purine analogue chemotherapy and to BRAF inhibitors combined w ...

VirtualMultiplexer transforms histology images into detailed cancer markers, streamlining diagnostics and enhancing patient outcomes through AI innovation.

PURPOSEThe role of consolidation radiotherapy in patients with primary mediastinal B-cell lymphoma (PMBCL) is controversial.METHODSThe IELSG37 trial, a randomized noninferiority study, aimed to assess ...

Researchers at the University of California San Diego (UCSD) have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain ...

Researchers discovered that a specific haplotype on chromosome 21 is linked to five inflammatory diseases, offering insights into potential new treatments.

Identification of distinct yolk sac-derived macrophage subpopulations in the fetal liver reveals their crucial role in shaping the hematopoietic niche, impacting erythropoiesis and granulopoiesis ...

Basophils are types of white blood cells that play a vital role in keeping the immune system functioning. Basophil tests can help diagnose many health concerns.