Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, ΔTrkA
The cell numbers were counted 24 h after coculture of leukemic cells in the presence of inhibitors. Cell viability was analyzed using the Annexin-V assay (BD Pharmingen, Heidelberg, Germany).
Small-molecule activators and inhibitors support a model in which S1P signaling must be inhibited to generate Müller glial progenitor cells-a key step in retinal regeneration. The presented results ...
Patients with ALK-rearranged non-small cell lung cancer (NSCLC) who are treated with ALK tyrosine kinase inhibitors (ALK TKIs) have better prognoses. In this case report, we provide evidence of a ...
Novel combination strategies are urgently needed to enhance efficiency of MWA. Conclusions: In this study, we found that the XIAP inhibitor AZD5582 modulates the immune microenvironment and inhibits ...
Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...
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