Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center believe that changes to a small patch of DNA within the enhancer region of the BCL11A gene may circumvent the ...

CRISPR-Cas9 targeting of the BCL11A enhancer may reactivate production of HbF and eliminate clinical manifestations of disease. New research findings are summarized in a short video. Video Summary of ...

BCL11A: Evidence for neuroprotective effect Date: September 14, 2021 Source: University of Bonn Summary: The neurotransmitter dopamine influences the activity of a wide variety of brain areas.

BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells. Nature Communications , 2015; 6: 5987 DOI: 10.1038/ncomms6987 Cite This Page : ...

CRISPR-Cas9 targeting of the BCL11A enhancer may reactivate production of HbF and eliminate clinical manifestations of disease. New research findings are summarized in a short video. Video Summary of ...

The researchers suspect that BCL11A plays a protective role for neurons. The study is now published in Cell Reports. ... For example, the target region was not the entire striatum, ...