New understanding of B cell mutation strategies could have implications for vaccines
A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...
Built-in safeguard in B cell populations could impact vaccine design
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies ...
Press Release: Sanofi to acquire Dren Bio’s bispecific myeloid cell engager for deep B-cell depletion, broadening immunology pipeline
Sanofi to acquire Dren Bio’s bispecific myeloid cell engager for deep B-cell depletion, broadening immunology pipelineDren Bio deep B-cell ...
News-Medical.Net on MSN20h
Study reveals how B cells safeguard high-affinity antibodies
A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...
Science Daily9h
New mechanism behind adaptive immunity revealed: It could impact how we design vaccines
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
Experimental treatment borrowed from blood cancer shows promise for pediatric brain tumors
In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts ...