A 42-year-old hypertensive and diabetic male presented to the hospital with complaints of severe weakness, decreased appetite and loss of weight for three months. He also developed difficulty of ...

Resistance to menin inhibitors often occurs in the initially sensitive MLL-rearranged (MLLr) leukemias. Here authors discover that inhibition of guanine nucleotide biosynthesis leads to myeloid ...

Aug. 21, 2024 — An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth. AML cells prevent the synthesis of proteins that ...

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