Solid tumors have dysfunctional vasculature that affects the delivery of nutrients to the TME. This limited availability of nutrients, including glucose, oxygen and amino acids, drives nutrient stress ...

Despite advancements in melanoma therapy, the prognosis remains unfavorable for many patients. The proteasome inhibitor MG132 has shown therapeutic potential through pathway regulation, yet its ...

For the in vitro component, cancer cell lines were exposed to electrical ... pulses correlated with increased levels of apoptosis, as measured by Annexin-V staining. The data suggest that the ...

Annexin V staining can be readily combined with immunophenotyping using fluorescently labeled antibodies to obtain cell specific apoptosis information ... In: Proceedings of the American Association ...

Meanwhile, we analyzed the effect of RUNX2 isoform II overexpression or knockdown on OSCC cell ferroptosis or apoptosis, cell proliferation and tumor growth.

The Annexin V-FITC Apoptosis assay results in (Figures 2(a ... the photothermal effect of TiO 2 NTs combined with NIR laser could efficiently destroy tumor cells without giving damage to surrounding ...

Further experimental results revealed that knocking down lncRNA Ubr5 can promote the apoptosis of ... buffer such that the cell density reached 1 × 106 cells/mL. A total of 100 μL of cells was added ...

The anti-tumor effect of CHK1 inhibitor using human PM cell lines were evaluated by MTT assay and annexin V assay ... CHK1 inhibitor had anti-tumor effect and induced apoptosis in a dose-dependent ...

Nitric oxide (NO) could normalise the inflammatory and desmoplasia phenotype of pancreatic stellate cells and triggers apoptosis sensitisation of PDAC ... enhanced desmoplasia and could be used in ...