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Proliferation of MCF-7 cells is estrogen dependent and antiestrogen sensitive. In the absence of estrogens or presence of antiestrogens MCF-7 cells arrest in the G1 phase of the cell cycle, and ...
Antiestrogen Therapy for Breast Cancer Modifies the Risk of Subsequent Cutaneous Melanoma. Cancer Prevention Research , 2011; 5 (1): 82 DOI: 10.1158/1940-6207.CAPR-11-0332 Cite This Page : ...
Antiestrogen therapy for breast cancer blocks these estrogen hormones. Three SERMs have been approved to prevent or treat breast cancer: Tamoxifen (Nolvadex, Soltamox) ...
Melanoma risk was 60 percent higher among those not taking antiestrogen therapy. Researcher cautions against widespread antiestrogen supplementation use. Study included 7,360 women with breast cancer.
Antiestrogen-resistant and triple-negative breast tumors pose a serious clinical challenge because of limited treatment options. We assessed global gene expression changes in antiestrogen ...
Anastrozole and fulvestrant used in combination might become the standard of care for hormone receptor-positive women with metastatic breast cancer.
Your Good Health: Antiestrogen drugs rarely used to treat erectile dysfunction. Dear Dr. Roach: I have a bad case of erectile dysfunction. I am 80 years old and otherwise in good health.
Although antiestrogen therapies targeting estrogen receptor (ER) α signaling prevent disease recurrence in the majority of patients with hormone-dependent breast cancer, a significant fraction of ...
Combined neoadjuvant antiestrogen therapy and anti–HER-2 dendritic cell vaccination increased pathologic complete response rate and decreased subsequent breast events among women with ER ...
Among postmenopausal women receiving estrogens with or without progestins for more than eight years, the prevalence of benign breast lesions increased by a factor of 1.70 (95 percent confidence ...
Randomized Phase II Study of Dulanermin in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Advanced Non–Small-Cell Lung Cancer Although antiestrogen therapies targeting estrogen receptor ...
Historically, breast cancer treatment is primarily composed of surgery, radiation, and some form of systemic therapy, and whether that can be chemotherapy, antiestrogen therapy, or targeted ...