Although fewer antibody fragments have entered the clinic than full-length monoclonal antibodies, proof-of-concept studies for these therapeutics remain the main hurdle. Tufts Center for the Study ...

To establish whether molecules other than scFv antibody fragments could be lipid-modified and inserted into cell membranes, we cloned the gene encoding human interleukin-2 (IL-2) into vector pLP2 ...

New active ingredients such as antibodies are usually tested individually in laboratory animals. Researchers have now developed a technology that can be used to test around 25 antibodies ...

To allow individual analysis of the properties of the antibodies from the complex plasma or tissue samples from the mice, the ...

You provide us the sequences of the fragments and we take care of the rest. Deliverables can be supernatant or purified antibodies. There is no additional set-up fee, and the cost of gene synthesis is ...

Versatility: They are highly versatile, modified into multiple formats, like single-chain variable fragments (scFvs), nanobodies, and bispecific antibodies. Scalability: Recombinant antibodies ...

This could only be rescued with antibodies directed against the MTBR and C-terminal-adjacent regions, implicating these tau species in synaptotoxicity. Tau fragments from trisomy 21 neurons inhibited ...

Axcynsis Therapeutics Pte Ltd. has described antibody-drug conjugates comprising an antibody or antigen-binding fragment targeting alkaline phosphatase placental type (ALPP) and/or alkaline ...