To determine whether increased androgen receptor protein concentration has a causal role in the hormone sensitive-to-hormone refractory transition, we introduced epitope-tagged wild-type AR cDNA ...
Androgen Receptor Targeted Agents: May be effective in LAR subtype of TNBC. Clinical Trials: Clinical trials are important in researching new treatments for TNBC. They offer patients to join ...
This indicates that GLP-1 receptor agonists lead to greater reduction in overall body fat than that in muscle mass, resulting in an overall body fat percentage decrease of around 4.5%.
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has described proteolysis targeting chimeric (PROTAC) compounds comprising a protein cereblon (CRBN) ligase binding moiety covalently linked to an ...
Haisco Pharmaceutical Group Co. Ltd. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an androgen receptor (AR) ...
Piperine stimulates the pain receptors of rats and other mammals, causing them to sneeze, cough, and "scurry away." A cluttered space is an ideal habitat for a rat, especially in garages where ...
His contributions to medicinal chemistry and bioorganic chemistry are many, particularly in the study of estrogen and androgen receptors, serine proteases and radiopharmaceuticals (see the related ...
Davis R Ingram; Lloye M Dillon; Dina Chelouche Lev; Alexander Lazar; Elizabeth G Demicco; Burton L Eisenberg; Todd W Miller ...
Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...
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