In a live event, Ganesh V. Raj, MD, PhD, discussed the drug-drug interactions and outcomes by disease volumes across ARPI trials in mHSPC.

Dose adjustments of antidiabetic agents may be required. CYP 3A4 inducers and inhibitors: May respectively increase or decrease clearance of corticosteroids necessitating dose adjustment.

The following is a summary of “Naldemedine Use and Healthcare Resource Utilization in Patients treated with Opioid Analgesics for Chronic Non-Cancer Pain: Results of a Real-world Study in the USA,” ...

Harrow , a leading North American eyecare pharmaceutical company, announced the execution of a five-year strategic supply and development ("SSD") agreement for TRIESENCE® (triamcinolone acetonide ...

Agents Inducing CYP3A Metabolism: Consider alternative therapeutic agents with less enzyme induction potential in patients when rifampin or other strong CYP3A4 inducers are indicated for concomitant ...

Cannabis (Cannabis sativa) is an herbal drug. It contains chemicals called cannabinoids, including delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The cannabinoids in cannabis work by ...

Agents Inducing CYP3A Metabolism: Consider alternative therapeutic agents with less enzyme induction potential in patients when rifampin or other strong CYP3A4 inducers are indicated for ...

Detailed price information for Intra-Cellular Ther (ITCI-Q) from The Globe and Mail including charting and trades.

Methods: The PBPK model for rifampicin, a potent CYP3A4 inducer, was developed and validated using human pharmacokinetic data. Subsequently, PBPK models for ‘victim’ drugs were constructed and ...