Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

5 Laboratory of Immunology, Faculty of Medicine, Vandoeuvre lès Nancy, France 6 Laboratory of Biochemistry, INSERM U724, Faculty of Medicine, Vandoeuvre lès Nancy, France Background: Homocysteine may ...

We analysed clinical trials of pharmacological interventions on patients with amyotrophic lateral sclerosis (ALS), and compared study quality and design features. The systematic review included ...

Department of Clinical Neurosciences, University of Cambridge Clinical School, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK N Robertson, Helen Durham Neuro-inflammatory Centre, Department of ...

Background: Efficient neuropsychological tests are needed to measure cognitive impairment in moderate to severe dementia. Objective: To examine construct validity of the Severe Impairment Battery ...

Dr R Barber, Institute for the Health of the Elderly, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, U.K. Tel +(0)191 256 3274 ext. 22986; fax +(0)191 219 5048; email ...

Department of Neuropathology, National Hospitals for Nervous Diseases, London, UK. The Lewy body is a distinctive neuronal inclusion that is always found in the substantia nigra and other specific ...

Department of Neurology, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester LE1 5WW, UK Correspondence to: Dr Y A Rajabally Department of Neurology, University Hospitals of ...

Correspondence to: Ryuji Sakakibara Department of Neurology Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670 Japan; sakakibarafaculty.chiba-u.jp If you wish to reuse any or all of this article ...

Correspondence to Professor Yoon-Ho Hong, Neurology, Neuroscience Research Institute, Medical Research Council, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae ...

Background Many common neurological disorders are associated with advancing chronological age, but their association with biological age (BA) remains poorly understood. Methods We studied 325 870 ...