Abnormal DNA methylation is strongly associated with cancer. The results suggest that, for cancer treatments to be effective, it may not be enough to simply target blocking LSD1's enzymatic activity.

Indeed, medical scientists are currently studying the connections between methylation abnormalities and diseases such as cancer, lupus, muscular dystrophy, and a range of birth defects that appear ...

An AI-powered blood test for detecting 12 common cancers has been awarded government funding for further clinical trials.

Researchers found that diseased tissue from patients with colorectal cancer had less DNA methylation than normal tissue from the same patients (Feinberg & Vogelstein, 1983). Because methylated ...

Researchers led by the University of Ulsan College of Medicine, Korea, have checked the performance of a noninvasive urinary DNA methylation test for bladder cancer diagnosis. Findings indicate ...

Outside of colon cancer, the methylation process also may have implications for resistance to chemotherapy and radiation, Dempsey says. "When the cells switch into this regenerative stem cell ...

GRAIL, Inc. (Nasdaq: GRAL), a healthcare company whose mission is to detect cancer early when it can be cured, will present new data highlighting the latest real-world evidence with the Galleri® multi ...

which is significantly associated with the development of ERneg breast cancer, and the methionine pathway, which affects protein methylation. In the current study, the investigators used ...

The American Cancer Society recommends people at average risk of colorectal cancer start screening at age 45, now several ...