Systemic sclerosis, or scleroderma, causes the hardening of skin and connective tissues. Often, the disease harms other ...

In some cases, it progresses slowly and is limited to the skin, while in others, it rapidly attacks internal organs such as ...

There are no tests that confirm the diagnosis of scleroderma. However, the following tests are useful in describing the prognosis of the 2 main forms of SSc, diffuse and limited, on the basis of ...

Diffuse scleroderma (extensive skin thickening proximal to the elbows and knees along with internal organ involvement) Scleroderma sine sclerosis (Raynaud's phenomenon and internal involvement ...