Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...
Erythropoietin, the protein that drives red blood cell formation, also induces tolerance in dendritic cells, leading to the ...
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the ...
Abcuro, Inc., a late-stage clinical biotechnology company developing potentially first-in-class immunotherapies designed to ...
Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic modalities such ...
Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...
The first-in-human clinical phase I trial assessing the feasibility and safety of WDVAX, an immunostimulatory ...
Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...
In peer-reviewed study, Prof. Alon Monsonego's lab finds that 'T helper' blood cells, abundant in 'super-centenarians' in ...